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  • ISU Room G501, Cholokashvili 3/5 Avenue, Tbilisi 0162, Georgia

Besik Kankia

Direction:Biophysics
Position:Associate Professor

M. S.: Department of Biological Physics, College of Physics, Georgia State University, Tbilisi,    Republic of Georgia, 1985; Ph. D. Institute of Biological PhysicsoftheRussianAcademyofSciences, Moscow, Russia, 1989 Thesis: “Hydration ofnucleicacids. Acousticanddensimetric investigation“;  Research experience: 1989 – 1991, Junior Scientist, Institute of Physiology, Tbilisi, Georgia; 1992 – 1993, Postdoctoral Fellow, Institute of Bioscience and Human Technology, Tsukuba, Japan; 1993 – 1997, Visiting Scientist, Max Planck Institute ofBiophysical Chemistry, Germany; 1997 – 2001, Research Associate, College of Pharmacy, University of Nebraska Medical Center; 2001 – 2004, Research Associate, Department ofBiochemistry, MolecularBiologyandBiophysics; 2004 – 2007, Research Associate, Department of Chemistry, University of Minnesota; 2007 – 2011, Research Scientist and Manager oftheBICF (Biomolecular Interactions CharacterizationFacility),  Department of Chemistry, The Ohio State University; 2011– present, Senior Research Scientist, Department of Chemistry andBiochemistry, The Ohio State University; 2011-presentAssociate Professor, Ilia State University.

Scientific interests / research interests
  • The secondary structures od DNA and RNA
  • Nucleic Acid quadruplexes
  • Molecular Diagnostics
  • DNA based nanomaterials
  • Evolution of genetic code
  • B. Kankia, “Quadruplex-and-Mg2+ (QMC) connection of DNA” Sci. Rep. 5, 12996; doi: 10.1038/srep12996 (2015).
  • B. Kankia, “Quadruplex priming amplification (QPA) for nucleic acid diagnostics” in RNA and DNA Diagnostics, V.A. Erdmann, S.Jurga, J.Barciszewski, Ed. Springer, 281-295 (2015).
  • T. Partskhaladze, A. Taylor, D. Gvarjaladze, L. Lomidze,B. Kankia, “Exponential quadruplex priming amplification for DNA-based isothermal diagnostics” Biopolymers 103,88-95 (2015).
  • Sh. Gogichaishvili, L. Lomidze,B. Kankia, “Quadruplex priming amplification combined with nicking enzyme for diagnostics” Anal.Biochem. 466, 44-48 (2014).
  • B. Kankia, “Tetrahelical Monomolecular Architecture of DNA: A New Building Block for Nanotechnology”J. Phys. Chem. B 118, 6134-6140 (2014).
  • N. M. Adams, K. Wang, A. Caprioli, L. Thomas, B. Kankia, F. Haselton, D. Wright, “Thermodynamic properties of quadruplex primers for highly versatile isothermal DNA amplification”Analyst 139, 1644-1652 (2014).
  • J. Mathias, R. Okyere, L. Lomidze, D.Gvarjaladze, K. Musier-Forsyth, B. Kankia,“Thermodynamic properties of quadruplex primers for highly versatile isothermal DNA amplification”Biophys. Chem. 185, 14-18 (2014).
  • Sh. Gogichaishvili, J. Johnson,D. Gvarjaladze, L. Lomidze,B. Kankia, “Isothermal amplification of DNA using quadruplex primers with fluorescent pteridine base analogue 3-methyl isoxanthopterin” Biopolymers 101, 583-590 (2014).
  • A. Taylor, A. Joseph, R. Okyere, Sh. Gogichaishvili, K. Musier-Forsyth, B. Kankia, “Isothermal quadruplex priming amplification for DNA-based diagnostics”Biophys. Chem. 171, 1-8 (2013).
  • J. Johnson, R. Okyere, A. Joseph, K. Musier-Forsyth, B. Kankia, “Quadruplex formation as a molecular switch to turn on intrinsically fluorescent nucleotide analogs” Nucleic Acids Res. 41, 220-28 (2013).
  • S. Maiti, B.I. Kankia, I.Khutsishvili, L. Marky “Melting behavior and ligand binding of DNA intramolecular secondary structures.” Biophys. Chem. 159, 162-71 (2011).
  • S. Kelley, S. Boroda, K. Musier-Forsyth, B.I. Kankia, “HIV-integraseaptamer folds into a parallel quadruplex: A thermodynamic study” Biophys. Chem. 155, 82-88 (2011).
  • B. I. Kankia, “Self-dissociative primers for nucleic acid amplification and detection based on DNA quadruplexes with intrinsic fluorescence” Anal.Biochem. 409, 59-65 (2011).

An extensive list of publications

Course Catalog

2020-2021 Year

Doctoral level

  • Research Seminar I
  • Research Seminar III
  • Biophysics of Nucleic Acids
  • Doctoral Seminar II

2019-2020 Year

Doctoral level

  • Research Seminar II
  • Doctoral Seminar I
  • Research Seminar I

2018-2019 Year

Doctoral level

  • Doctoral Seminar II
  • Biophysics of Nucleic Acids
  • Doctoral Seminar I

2016-2017 Year

Master's level

  • Medical Physics

Doctoral level

  • Research Seminar
  • Biophysics of Nucleic Acids

2015-2016 Year

Doctoral level

  • Research Seminar

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