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  • lali_shanshiashvili@iliauni.edu.ge
  • G202

Lali Shanshiashvili

Direction:Neurochemistry
Position:Full Professor

Lali Shanshiashvili  graduated Tbilisi State University  in 1987. She continued research at Institute of Physiology of Georgian academy of Sciences in Tbilisi (1987-2013), was engaged in biochemistry. Lali Shanshiashvili got the degree of a candidate of biological sciences in 1991 and the degree of a doctor of sciences in 2004. 2000-2008 she had collaborations with Laboratory of Surface Biochemistry, University of Basel, Switzerland and Centre for Molecular Recognition, Collegium Basilea (Institute of Advanced Study), Basel, Switzerland. Since 2006 she is associate professor of Ilia State University.

Her main research interest lies in the study of the effect of myelin basic protein charge isomers and their peptide fragments on the  primary glial cells; glutamate receptors; macrophage plasticity; protein-lipid interactions; apoptosis; the metabolic imbalance of immune cells during genetic diseases, in particular during cystic fibrosis

Since 2000 she is academic Secretary of the Journal of Biological Physics and Chemistry (JBPC) http://www.amsi.ge/jbpc/.

  1. Shanshiashvili L., Tsitsilashvili E., Dabrundashvili N., Kalandadze I., Mikeladze D. Metabotropic glutamate receptor 5 may be involved in macrophage plasticity. Biol.Res. 14:50(1):4.doi: 10.1186/s40659-017-0110-2. 2017
  2. G.Tevzadze, L.Shanshiashvili, D.mikeladze. Children with epilepsy and autistic spectrum disorders show similarly high levels of urinary p-cresol. The Journal of Biological Physics and Chemistry 17, (2017) 77-80.
  3. E.O. Tsitsilashvili, L.V. Shanshiashvili and D.G. Mikeladze. Macrophages—cells with broad potential. The Journal of Biological Physics and Chemistry V 16 (4), (2016) 162–166.
  4. L.Shanshiashvili, I.Kalandadze , J.Ramsden, D.Mikeladze. Different isoforms of  deiminated myelin basic protein have different adsorption capacities to the myelin lipids.  Journal of Biological Physics and Chemistry 14(3), pp.57-63,  2014.
  5. Shanshiashvili LV, Kalandadze IV, Ramsden JJ, Mikeladze DG. Adhesive Properties and Inflammatory Potential of Citrullinated Myelin Basic Protein Peptide 45-89. Neurochemical Research. 37, no 9:1959-1966, 2012.
  6. Shanshiashvili LV, Dabrundashvili N, Natsvlishvili N, Kvaratskhelia E, Zhuravliova E, Barbakadze T, Koriauli S, Maisuradze E, Topuria T, Mikeladze DG. mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes. Molecular Immunology 51, no 3-4:310-315, 2012.
  7. Zhuravliova E, Barbakadze T, Jojua N, Zaalishvili E, Shanshiashvili L, Natsvlishvili N, Kalandadze I, Narmania N, Chogovadze I, Mikeladze D. Synaptic and Non-Synaptic Mitochondria in Hippocampus of Adult Rats Differ in Their Sensitivity to Hypothyroidism. Cellular and Molecular Neurobiology 32:1311–1321, 2012.
  8. Shanshiashvili L. N. Narmania T. Barbakadze  E. Zhuravliova   N. Natsvlishvili J. Ramsden, D. G. Mikeladze. S-Nitrosylation Decreases the Adsorption of H-Ras in Lipid Bilayer and Changes Intrinsic Catalytic Activity. Cell Biochemistry and Biophysics.  59:191–199, 2011.
  9. Shanshiashvili L., Suknidze N., Machaidze G., Mikeladze D., Ramsden J. “Adhesion and  clustering of charge isomers of myelin basic protein at model myelin membranes“.  Archives of Biochemistry and Biophysics. 419, 170-177, 2003.

Course Catalog

One-cycle higher educational program

  • Biochemistry (ENG)
  • Cardiovascular System & Blood (ENG)
  • Endocrine and Genitourinary Systems (ENG)
  • Respiratory & Digestive Systems (ENG)

Bachelor’s level

  • Fundamentals of Immunology

Master’s level

  • Molecular immunology
  • Biochemistry of Systems and Metabolomics
  • Design of Medicines and Deliberate Supply

One-cycle higher educational program

  • Biochemistry (ENG)
  • Cardiovascular System & Blood (ENG)
  • Endocrine & Urogenital Systems (Endocrine & Urogenital Systems) (ENG)
  • Respiratory & Digestive Systems (ENG)

Bachelor’s level

  • Biochemistry
  • Principles of Immunology

Master’s level

  • Molecular Bases of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular immunology
  • Biochemistry of Systems and Metabolomics

Doctoral level

  • Doctoral Seminar II

 

Course Catalog

2020-2021 Year

One-cycle higher educational program

  • Biochemistry (ENG)
  • Body Systems Structure & Function I (Cardiovascular System & Blood) (ENG)
  • Body Systems Structure & Function II (Respiratory & Digestive Systems) (ENG)
  • Body Systems Structure & Function III (Endocrine & Urogenital Systems) (ENG)
  • Body Systems Structure & Function I (ENG)
  • Body Systems Structure & Function II (ENG)
  • Body Systems Structure & Function III (ENG)

Bachelor’s level

  • Biochemistry
  • Principles of Immunology

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular immunology
  • Biochemistry of Systems

Doctoral level

  • Doctoral Seminar I

2019-2020 Year

One-cycle higher educational program

  • Biochemistry I (ENG)

Bachelor’s level

  • Biochemistry
  • Proteins-Multifunctional Molecules

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry I (ENG)
  • Molecular immunology
  • Biochemistry of Systems

2018-2019 Year

Bachelor’s level

  • Biochemistry
  • Principles of Immunology
  • Proteins-Multifunctional Molecules

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular immunology
  • Biochemistry of Systems

2017-2018 Year

Bachelor’s level

  • Biochemistry
  • Principles of Immunology

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular immunology
  • Biochemistry of Systems

2016-2017 Year

Bachelor’s level

  • Biochemistry
  • Proteins-Multifunctional Molecules
  • Principles of Immunology

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular immunology
  • Neuropharmacology/Psychopharmacology and Mechanisms of Drugs Interaction
  • Biochemistry of Systems

2015-2016 Year

Bachelor’s level

  • Biochemistry
  • Proteins-Multifunctional Molecules

Master’s level

  • Selected Topics of Allergology
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Systems

2014-2015 Year

Bachelor’s level

  • Biochemistry
  • Proteins-Multifunctional Molecules
  • Principles of Immunology

Master’s level

  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Systems

2013-2014 Year

Bachelor’s level

  • Biochemistry
  • Principles of Immunology

Master’s level

  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Systems

2012-2013 Year

Bachelor’s level

  • Biochemistry

Master’s level

  • Apoptosis and Cell Proliferation
  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Neural Tissue
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue
  • Master's Thesis -
  • Biochemistry of Systems

Doctoral level

  • Principles of Modification of Biological Catalysis

2011-2012 Year

Bachelor’s level

  • Achievements of Modern Biology

Master’s level

  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Systems

2010-2011 Year

Master’s level

  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular immunology
  • Biochemistry of Systems
  • Apoptosis and Cell Proliferation
  • Biochemistry of Neural Tissue

Doctoral level

  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Principles of Modification of Biological Catalysis

2009-2010 Year

Bachelor’s level

  • General Biochemistry

Master’s level

  • Favorite Chapters of Biochemistry
  • Molecular Biology Research Methods, Principles of Bioinformatics and Biotechnology
  • Molecular Principles of Oncology

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