Direction:Medical Biological Research
Position:Associate Professor
Ivane Abiatari completed his medical education in Tbilisi in 2003, after which he continued his studies at the Ph.D. level at the University of Heidelberg, European Pancreas Center (Germany). From 2007, he continued his research and clinical work at the Technical University of Munich (Germany). In 2010, he defended his Ph.D. thesis within the joint doctoral program of I. Javakhishvili Tbilisi State University and the Technical University of Munich. The thesis title is “Characterization of perineural invasion of pancreatic cancer.” In 2011, he obtained the qualification of a General Surgeon. From 2007 to 2013, he worked as a Postdoc and visiting doctor at the University Hospital of Klinikum rechts der Isar (Technical University of Munich). Since 2013, Ivane Abiatari has been an Associate Professor at Ilia State University. In 2018, he became the director of the Institute of Medical and Public Health Research, and since 2020 he has been appointed as the head of the School of Medicine. Under his supervision, Ilia State University operates an English-language MD educational program and an English-language Ph.D. program in medicine. He holds a Specialist Certificate in Medical Education (AMEE).
In 2006 – 2010, Ivane Abiatari received research scholarships from “Boehringer Ingelheim,” DAAD, and “Fritz Thyssen” foundations. In 2017, he was awarded the Best Young Scientist of Georgia (Rustaveli Science Foundation). In 2017 – 2019, he was a beneficiary of the GIZ/CIM program. In 2022, Ivane Abiatari obtained the Fulbright scholarship for Exchange Scholars (Harvard Medical School, Boston, MA).
Ivane Abiatari has published more than 30 papers in peer-reviewed journals.
h-index = 12 (SCOPUS).
Scientific interests / research interests
- Cancer research
- Pancreatic adenocarcinoma
- Experimental surgery
- Translational medicine
- Molecular bio-medicine
Publications
- Ogiya D, Chyra Z, Verselis S, et al. Identification of disease-related aberrantly spliced transcripts in myeloma and proposing strategies to target these alterations by RNA-based therapeutics. Blood Cancer Journal. 2023;22-BCJ-0066RR
- Ramishvili N, Chachua I, Zurmukhtashvili M, Abiatari I, Marks L, Dugashvili G. Progression of primarily untreated desomorphine drug induced jaw osteonecrosis: A case report. Special Care in Dentistry. 2022.
- Leinenkugel G, Kong B, Raulefs S, et al. Sca-1 is a marker for cell plasticity in murine pancreatic epithelial cells and induced by IFN-β in vitro. Pancreatology. 2022;22(2):294-303.
- Kakabadze E, Makalatia K, Bakuradze N, et al. Gut health of children with autism spectrum disorder. World Academy of Sciences Journal. 2022;4(4):1-9.
- Gotsadze G, Mirzikashvili N, Kekelidze D, et al. The State of Public Health Education and Science During and After the Fall of the Soviet Union: Achievements, Remaining Challenges, and Future Priorities. Frontiers in Public Health. 2022;10.
- Adamia S, Bhatt S, Wen K, et al. Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma. Leukemia. 2022;36(4):1088-1101.
- Bakuradze N, Merabishvili M, Makalatia K, et al. In Vitro Evaluation of the Therapeutic Potential of Phage VA7 against Enterotoxigenic Bacteroides fragilis Infection. Viruses. 2021;13(10):2044.
- Zurmukhtashvili M, Machavariani A, Dugashvili G, et al. Mesenchymal stem cell transplantation attenuates growth of chemotherapy treated oral squamous cell carcinoma in an animal model. Journal of Oral Pathology & Medicine. 2020;49(7):655-664.
- Shanava K, Javor S, Kerkadze V, Abiatari I, Weber G. Protective effects of postconditioning in transvaginally created pneumoperitoneum. Experimental and therapeutic medicine. 2020;19(6):3861-3866.
- Adamia S, Abiatari I, Amin SB, et al. The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma. Leukemia. 2020;34(1):167-179.
- Ogiya D, Müller L, Verselis SJ, et al. Aberrant RHAMM Splicing in Multiple Myeloma (MM) and Its Implications for Immunotherapy. Blood. 2019;134:1804.
- Pipia I, Kenchadze G, Demetrashvili Z, et al. Gallbladder agenesis: A case report and review of the literature. International journal of surgery case reports. 2018;53:235-237.
- Abiatari I, Midelashvili T, Motsikulashvili M, Tchavtchavadze A, Tawfeeq S, Amiranashvili I. OVEREXPRESSED PROGENITOR GENE CSF1R IN PANCREATIC CANCER TISSUES AND NERVE INVASIVE PANCREATIC CANCER CELLS. Georgian Medical News. 2018(285):96-100.
- Mardaleishvili K, Kakabadze Z, Machavariani A, et al. Benign osteoblastoma of the mandible in a 12‑year‑old female: A case report. Oncology letters. 2014;8(6):2691-2694.
- Kakabadze Z, Abiatari I, Makashvili M, Karashvili L, Kakabadze A. Anatomical justification for the use of human placenta as a host for in vivo cell and tissue transplantation. Asian Journal of Pharmacy, Nursing and Medical Sciences (ISSN: 2321–3639) Volume 02–Issue 01, February 2014. 2014.
- Sukhitashvili N, Tsiklauri M, Zurmukhtashvili M, et al. Autoserum Expansion of Mouse Dental Pulp and Bone Marrow Mesenchymal Stem Cells. Новини стоматології. 2013(1):83-86.
- Klose T, Abiatari I, Samkharadze T, et al. The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer. Pancreatology. 2012;12(4):350-357.
- De Oliveira T, Abiatari I, Raulefs S, et al. Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype. Molecular cancer. 2012;11(1):1-10.
- Herner A, Sauliunaite D, Michalski CW, et al. Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras‐MAPK signaling. International journal of cancer. 2011;129(10):2349-2359.
- Kong B, Michalski C, Hong X, et al. AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling. Oncogene. 2010;29(37):5146-5158.
- Abiatari I, Esposito I, Oliveira TD, et al. Moesin‐dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer. Journal of cellular and molecular medicine. 2010;14(5):1166-1179.
- Jiang X, Abiatari I, Kong B, et al. Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 in pancreatic cancer. Pancreatology. 2009;9(1-2):165-172.
- Abiatari I, Kiladze M, Kerkadze V, Friess H, Kleeff J. Expression of YPEL1 in pancreatic cancer cell lines and tissues. Georgian medical news. 2009(175):60-62.
- Abiatari I, Gillen S, DeOliveira T, et al. The microtubule-associated protein MAPRE2 is involved in perineural invasion of pancreatic cancer cells. International journal of oncology. 2009;35(5):1111-1116.
- Abiatari I, DeOliveira T, Kerkadze V, et al. Consensus transcriptome signature of perineural invasion in pancreatic carcinoma. Molecular cancer therapeutics. 2009;8(6):1494-1504.
- Michalski C, Herner A, Sauliunaite D, et al. AMPA RECEPTOR ANTAGONISM INHIBITS PANCREATIC CANCER GROWTH. Pancreas. 2008;37(4):485.
- Erkan M, Michalski CW, Rieder S, et al. The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clinical gastroenterology and hepatology. 2008;6(10):1155-1161.
- Zhang W, Erkan M, Abiatari I, et al. Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells. Cancer biology & therapy. 2007;6(2):218-227.
- Esposito I, Kleeff J, Abiatari I, et al. Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer. Journal of clinical pathology. 2007;60(8):885-895.
- Esposito I, Kleeff J, Abiatari I, et al. cIAP2 Overexpression is an early event in pancreatic cancer progression. Journal of Clinical Pathology. 2006.
- Abiatari I, Kleeff J, Li J, Felix K, Büchler MW, Friess H. Hsulf-1 regulates growth and invasion of pancreatic cancer cells. Journal of clinical pathology. 2006;59(10):1052-1058.
- Li J, Kleeff J, Abiatari I, et al. Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer. Molecular cancer. 2005;4(1):1-14.
Book chapters
- Abiatari I, DeOliveira TA, Maldonado RG. (2007): Stem cell isolation, identification and manipulation techniques in vitro. “In”: Ogliari KS, Franзa JP, Ferreira AT. ”Stem Cells: Science, Technology and Ethics”. Rio de Janeiro – Revinter.
- Abiatari I. (2007): ”Molecular diagnostics in clinical oncology” “In” Osinsky SP, Gluzman DF. “Molecular Diagnostics of Cancer”. Kyiv – Dia.
Current Courses |
Course Catalog |
||
|---|---|---|---|
|
2020-2021 Year Doctoral level
2018-2019 Year Bachelor’s level
Doctoral level
2017-2018 Year Bachelor’s level
Doctoral level
2016-2017 Year Bachelor’s level
Doctoral level
2015-2016 Year Bachelor’s level
Doctoral level
2014-2015 Year Bachelor’s level
Doctoral level
2013-2014 Year Doctoral level
|