SCHOOL OF NATURAL SCIENCES AND MEDICINE
ILIA STATE UNIVERSITY

School of Natural Sciences and Engineerings. Professor Emeritus

Full Professor at the Institute of Chemical Biology





In 1972 she finished Tbilisi State University, Faculty of Biology, Specialty “Cytology and Histology”; in 1975 – TbilisiI. Chavchavadze State Institute of Foreign Languages, Specialty “French Language”; in 1878 – aspirant courses in the Institute of Brain, USSR Medical Academy of Science, Specialty “Neuroanatomy. Brain Ultrastructure” (Moscow). In 1980 she became candidate of Biological Science (Topic of dissertation “Synapsoarchitecture of projective, intrahemispheric and interhemispheric connections in projective and associative areas of brain” and in 1996  she got the degree Doctor of Biological Science  (Topic of dissertation: “The effect of different forms of hypokinesia on limbic, extrapyramidal and neocortical regions of rat brain”). Worked at Beritashvili Institute of Physiology. Her current positions are full professor at Ilia State University and head of lab at Beritashvili center of Experimental Biomedicine. She had trainings and performed research in Prague University, Institute of Brain, Bulgarian Academy of Science, Institute of Molecular Biology of Kuopio University, Iowa State University, USA. The main directions of the research are the structure and ultrastructure of brain in norm and under different pathological conditions (forms of experimental epilepsy, inhalant chronic misuse, different forms of stress and hypokinesia, social isolation) and neuronal secretion. She is author of about 100 scientific publications, invited  professor in several universities of Georgia.

Scientific interests / research interests

  • Neuroscience;
  • Neurohistology, Neurocytology, Neuron Ultrastructure;
  • Nanoneuroarchitecture;
  • Cell Biology (Cytology);
  • Neuron Secretion (Porosome Structure and Molecular Composition);
  • Functional Neuroanatomy;
  • Nanobiology/Nanomedicine:
  • Atomic Force Microscopy of Living Cell (Neuron);
  • Science Education for New Civic Engagement and Responsibility

Featured publications:

• Mzia G. Zhvania, Nadezhda J. Japaridze, Mariam G. Qsovreli, Vera G. Okuneva, Arkadi G. Surmava, Tamar G. Lordkipanidze. Electron Microscopic Morphometry of Isolated Rat Brain Porosome Complex. Neuroscience Research, 2015 (Accepted for Publication).
• Mzia G. Zhvania, Tamar Z. Bikashvili, Nadezhda J. Japaridze, Ilia I. Lazrishvili, Mariam Ksovreli. White noise and neuronal porosome complex: transmission electron microscopic study. DISCOVERIES 2014, Jul-Sep, 2(3): e25. DOI: 10.15190/d.2014.17.
• Mzia G. Zhvania, Nadezhda J. Japaridze, Mariam G, Qsovreli, Vera G. Okuneva, Arkadi G. Surmava, Tamar G. Lordkipanidze. The Neuronal Porosome Complex in Mammalian Brain: A Study Using Electron Microscopy. Chapter: NanoCellBiology: Multimodal Imaging in Biology and Medicine. Editors: Jena B.P., Taatjes D.J. Pan Stanford Publishing Pte. Ltd. (Cover: Neuronal Porosome Complex) (2013 September), 45-55.
• Kotaria N, Kiladze M, Zhvania MG, Japaridze NJ, Bikashvili T, Solomonia RO, Zhvania M, Bolkvadze T. The protective effect of Myo-inositol on hippocampal cell loss and structural alterations in neurons and synapses triggered by kainic acid-induced status epilepticus, Cellular & Molecular Neurobiol. 2013, 33, 5, 659-671.
• Lordkipanidze T, Bikashvili T, Japaridze N, Zhvania M. The Effect of kainic acid on hippocampal dendritic spine motility at the early and late stages of development, Micron (2013), 49, 28-32.
• Japaridze NJ, Okuneva VG, Qsovreli MG, Surmava AG, Lordkipanidze TG, Kiladze MT, Zhvania MG. Hypokinetic stress and neuronal porosome complex in the rat brain: the electron microscopic study. Micron, 2012, 43, 9, 948-954.
• Zhvania MG, Chilachava LR, Japaridze NJ, Gelazonia LK, Lordkipanidze TG. Immediate and persisting effect of toluene chronic exposure on hippocampal cell loss in adolescent and adult rats. Brain Res. Bull. 2012, 87, 2, 187-192.
• Cho WJ, Lee JS, Zhang L, Ren G, Shin L, Manke CW, Potoff J, Kotaria N, Zhvania MG, Jena BP. Membrane-directed molecular assembly of the neuronal SNARE complex. J. Cell Mol Med. 2011,15, 1 13-17.
• Cho WJ, Jeremic A, Rognlien KT, Zhvania MG, Lazrishvili I, Tamar B, Jena BP.Structure, isolation, composition and reconstitution of the neuronal fusion pore. Cell Biol Int 2004, 28, 10, 699-708.

 Books

Leader and Leadership. 2009, Tbilisi, Georgia (Financed by USAID)

Articles in magazines

Nanomedicine. Review 2014. Actual Topics on Woman Health (Georgian Medical Women’s Association), 5, 80-132.

An extensive list of publications

Current Courses

Course Catalog

Bachelor’s level

  • Cell Biology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Bachelor’s level

  • Cell Biology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Doctoral Seminar II
  • Doctoral Seminar I

2020-2021 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Doctoral Seminar I
  • Modern Methods of Neurobiological Research

2019-2020 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Nanotechnological Approaches in Neurobiology
  • Research Seminar I

2018-2019 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Research Seminar I
  • Nanotechnologies for Nanomedicine
  • Nanotechnological Approaches in Neurobiology
  • Neuron Structure in Different Neuropathologies
  • Doctoral Seminar II
  • Structural Neuroimaging
  • Functional Neuroanatomy
  • Modern Methods of Neurobiological Research
  • Neuron Structure in Different Neuropathologies
  • Doctoral Seminar I
  • Doctoral Seminar II

2017-2018 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Research Seminar II
  • Doctoral Seminar I

2016-2017 Year

Bachelor’s level

  • Cytology

Master’s level

  • Functional Neuroanatomy

Doctoral level

  • Research Seminar I
  • Doctoral Seminar II

2015-2016 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Nanotechnological Approaches in Neurobiology
  • Modern Methods of Neurobiological Research
  • Doctoral Seminar I

2014-2015 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Modern Methods of Neurobiological Research

2013-2014 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Modern Methods of Neurobiological Research
  • Nanotechnological Approaches in Neurobiology

2012-2013 Year

Bachelor’s level

  • Cytology

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine
  • Functional Neuroanatomy

Doctoral level

  • Modern Methods of Neurobiological Research
  • Nanotechnological Approaches in Neurobiology

2011-2012 Year

Bachelor’s level

  • Achievements of Modern Biology

Master’s level

  • Cellular Principles of Functional Neuroanatomy and Synaptic Plasticity

Doctoral level

  • Modern Methods of Neurobiological Research

2010-2011 Year

Master’s level

  • Nanoscience: Principles of Nanobiology and Nanomedicine

2009-2010 Year

Bachelor’s level

  • Human anatomy

Master’s level

  • Cellular Principles of Functional Neuroanatomy and Synaptic Plasticity