Direction:Oncology
Position:Associate Professor
After graduating Tbilisi State Medical University on 2003, he studed in oncology residency in N.N Petrov Oncology Research Institute. Saint-Petersburg, Russia (2003-2007).
From 2008 he works as oncologist in Surgical Centre after St. Nikolozi. Kutaisi, Georgia, Department of Radio-oncology at The University Clinic and Breast Cancer Unit at S.Khechinashvili University Hospital. (Tbilisi, Georgia)
01/2009 – 09/2016 He was the head of Oncology Department at Aversi Hospital and 09/2016 – 12/2020 head of the Oncology and Hematology Department at Research Institute of Clinical Medicine after Ac. F. Todua. (Tbilisi, Georgia)
Since 12/2020 Ivane Kiladze works as head of Clinical Oncology Department at CMC-Caucasus Medical Centre.
Since 04/2017 he is invited lecture at Tbilisi State Medical University AMD program.
As medical oncologist he participated in observership programs in various cancer centers (Turkey, Israel, Switzerland, Spain). 04/2018 – 05/2019 he studied in Zurich University and ESO Certificate of Advanced Studies in Lung Cancer Program. (Zürich, Switzerland)
He is principal investigator of more then 10 phase II and III clinical studies.
On 2021 he depends his PhD at Ivane Javakhishvili Tbilisi State University. He is a member of various research groups and actively involved in oncology research worldwide.
Scientific interests / research interests
Molecular biology of cancer and gene profiling, immunotherapy of solid tumor, lung cancer treatment, breast cancer in young women, cancer treatment in resource restricted countries.
Featured publications
- Ivane Kiladze, Elene Mariamidze, Branislav Jeremic. Lung Cancer in Georgia. Journal of Thoracic Oncology Vol. 15 No. 7: 1113-1118. doi.org/10.1016/J.JTHO.2020.02.030
- Kiladze, I., Mariamidze, E., Baramidze, A., Lomidze, M., Meladze, K., & Jeremic, B. (2021). Molecular profiling and characteristics of non-small-cell lung cancer patients in Georgia. Future oncology (London, England), 17(27), 3585–3594. https://doi.org/10.2217/fon-2021-0177
- Kiladze I, Mariamidze E, Jeremic B. Real-World Treatment Patterns of Lung Cancer in a Resource-Restricted Country: the Experience of Georgia. Health Serv Insights. 2021 Nov 3;14:11786329211055296. doi: 10.1177/11786329211055296. PMID: 34776730; PMCID: PMC8573520.
An extensive list of publications
- I.Kiladze, N. Sharikadze, T. Esakia. Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients Receiving Oxaliplatin-Based Combination Chemotherapy- CapeOX Annals of Oncology, Volume 27, Issue suppl_6, 1 October 2016, 504P. https://doi.org/10.1093/annonc/mdw370.52
- I. Kiladze, A. Mariamidze, M. Mchedlishvili, K. Tsomaia, F. Todua. Comparison of Breast Cancer subtypes between young and elderly women. Annals of Oncology, Volume 28, Issue suppl_5, 1 September 2017. https://www.annalsofoncology.org/article/S0923-7534(20)38954-7/fulltext
- L. Katselashvili, I. Kiladze, M. Katcharava, N. Jokhadze et al. Randomized Prospective Study: Paclitaxel every-3-weeks versus weekly Paclitaxel and versus weekly Vinorelbin in metastatic Breast cancer. The Breast [2018] https://www.thebreastonline.com/article/S0960-9776(17)30697-5/fulltext.
- N. Jokhadze, I. Kiladze, L. Katselashvili et al. Optimal chemotherapy regimen for concurrent chemo-radiotherapy of locally advanced unresectable stage III non-small cell lung cancer (NCSLC). Journal of Thoracic Oncology. Vol. 13 No. 4S: S66–S67 [2018] http://www.jto.org/article/S1556-0864(18)30394-0/fulltext.
- I. Kiladze, V. Kuchava, N. Joxadze, L. Katselashvili et l. Primary surgery followed by chemotherapy versus definitive concurrent chemoradiotherapy in locally advanced non-small cell lung cancer. Journal of Thoracic Oncology. April 2018. Volume 13, Issue 4, Supplement, Pages S66–S67 [2018] http://www.jto.org/article/S1556-0864(18)30395-2/pdf/
- T. Esakia, B. Metonidze, L Turkiashvili, E. Dgebuadze, L. Katselashvili, T. Melkadze, I. Kiladze. Perioperative chemotherapy with FLOT versus other regimens for resectable gastric cancer. Annals of Oncology. Volume 30 Supplement 4, July 2019. https://doi.org/10.1093/annonc/mdz155.219
- Branislav JEREMIC, Pavol DUBINSKY, Marta JEREMIC, Ivane KILADZE, Gökhan ÖZYIGIT. Optimal Dose of Cisplatin (CDDP) Given Concurrently with Radiotherapy (RT) in Locally Advanced Squamous Cell Head and Neck Cancer (SQC HNC). Turkish Journal of Oncology [2020] http://onkder.org/pdf/pdf_TOD_1138.pdf
- Branislav Jeremic, Ivane Kiladze, Marta Jeremic, Nenad Filipovic. Radiotherapy target volume for limited disease small cell lung cancer: good news from dark side of moon. Annals of Translational Medicine. Vol 8, No 14 (July 2020)https://atm.amegroups.com/article/view/39550/html
- I. Kiladze, E. Mariamidze, B.Jeremic. Challenging pretreatment aspects of lung cancer in Georgia. Journal of Lung Health and Diseases [2020] https://www.lungdiseasesjournal.com/articles/challenging-pretreatment-aspects-of-lung-cancer-ingeorgia.html
- Ivane Kiladze, Merab Kiladze, Branislav Jeremic. Neoadjuvant Treatment for Resectable, Stage IIIA Non-Small Cell Lung Cancer. Cancer Therapy and Oncology International Journal CTOIJ (Volume 17 Issue 5) 10.19080/CTOIJ.2021.17.555973 /https://juniperpublishers.com/ctoij/pdf/CTOIJ.MS.ID.555974.pdf
- E. Mariamidze, I. Kiladze, B. Jeremic. Current State and Challenges of Lung Cancer Treatment in Georgia. Journal of Thoracic Oncology16(3):S326. March 2021. DOI:10.1016/j.jtho.2021.01.501
- Branislav JEREMIC, Ivane KILADZE Gökhan ÖZYİĞİT, Nenad FILIPOVIĆ, Pavol DUBINSKY. Novel Technological Aspects of Radiation Therapy in Head and Neck Cancer. Turk J Oncol 2021;36(2):236–46. DOI:10.5505/tjo.2020.2579
- Kopadze, S., Shoshiashvili, I., Dumbadze, A., Tkemaladze, T., & Kiladze, I. (2021). Neuroendocrine pancreatic tumor in a patient with dual diagnosis of tuberous sclerosis complex and basement membrane disease: A case report and review of the literature. Radiology case reports, 16(11), 3581–3588. https://doi.org/10.1016/j.radcr.2021.08.041
- Jeremić B., Filipović N., Milisavljević S., Kiladze I. (2021) Radiation Oncology of Lung Cancer: Why We Fail(ed) in Clinical Research?. In: . Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2021_282
- Ivane KILADZE,Gökhan ÖZYİĞİT,Pavol DUBINSKY,Nenad FILIPOVIC,Branislav JEREMIC. Systemic Therapy in Recurrent or Metastatic Squamous Cell Head and Neck Cancer. Turk J Oncol 2021;36(4):519–28 doi: 10.5505/tjo.2021.2849
- Jeremic B., Kiladze I., Milisavljevic S. (2021) Multimodality Treatment of Stage IIIA/N2 NSCLC: Why Always NO to Surgery?. In: . Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2021_275
- Jeremić B., Dubinsky P., Milisavljević S., Kiladze I. (2021) Combined Radiation Therapy and Chemotherapy as an Exclusive Treatment Option in Locally Advanced Inoperable Non-small Cell Lung Cancer. In:Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2021_277
- Jeremić B., El-Bassiouny M., Ghali R., Kiladze I., Abdel-Wahab S. (2021) Role of Thoracic Radiation Therapy in Extensive Disease Small Cell Lung Cancer. In: Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2021_279
- Jeremić B., Kiladze I., Dubinsky P., Milisavljević S. (2021) Radiation Therapy in Limited Disease Small Cell Lung Cancer. In: Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2021_278
- Edelman MJ, Dvorkin M, Laktionov K, Navarro A, Juan-Vidal O, Kozlov V, Golden G, Jordan O, Deng CQ, Bentsion D, Chouaid C, Dechev H, Dowlati A, Fernández Núñez N, Ivashchuk O, Kiladze I, Kortua T, Leighl N, Luft A, Makharadze T, Min Y, Quantin X; DISTINCT study investigators. Randomized phase 3 study of the anti-disialoganglioside antibody dinutuximab and irinotecan vs irinotecan or topotecan for second-line treatment of small cell lung cancer. Lung Cancer. 2022 Mar 4;166:135-142. doi: 10.1016/j.lungcan.2022.03.003. Epub ahead of print. PMID: 35278766.
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