Direction:Neurochemistry
Position:Full Professor
Lali Shanshiashvili graduated Tbilisi State University in 1987. She continued research at Institute of Physiology of Georgian academy of Sciences in Tbilisi (1987-2013), was engaged in biochemistry. Lali Shanshiashvili got the degree of a candidate of biological sciences in 1991 and the degree of a doctor of sciences in 2004. 2000-2008 she had collaborations with Laboratory of Surface Biochemistry, University of Basel, Switzerland and Centre for Molecular Recognition, Collegium Basilea (Institute of Advanced Study), Basel, Switzerland. Since 2006 she is associate professor of Ilia State University.
Her main research interest lies in the study of the effect of myelin basic protein charge isomers and their peptide fragments on the primary glial cells; glutamate receptors; macrophage plasticity; protein-lipid interactions; apoptosis; the metabolic imbalance of immune cells during genetic diseases, in particular during cystic fibrosis
Since 2000 she is academic Secretary of the Journal of Biological Physics and Chemistry (JBPC) http://www.amsi.ge/jbpc/.
Scientific interests / research interests
- Shanshiashvili L., Tsitsilashvili E., Dabrundashvili N., Kalandadze I., Mikeladze D. Metabotropic glutamate receptor 5 may be involved in macrophage plasticity. Biol.Res. 14:50(1):4.doi: 10.1186/s40659-017-0110-2. 2017
- G.Tevzadze, L.Shanshiashvili, D.mikeladze. Children with epilepsy and autistic spectrum disorders show similarly high levels of urinary p-cresol. The Journal of Biological Physics and Chemistry 17, (2017) 77-80.
- E.O. Tsitsilashvili, L.V. Shanshiashvili and D.G. Mikeladze. Macrophages—cells with broad potential. The Journal of Biological Physics and Chemistry V 16 (4), (2016) 162–166.
- L.Shanshiashvili, I.Kalandadze , J.Ramsden, D.Mikeladze. Different isoforms of deiminated myelin basic protein have different adsorption capacities to the myelin lipids. Journal of Biological Physics and Chemistry 14(3), pp.57-63, 2014.
- Shanshiashvili LV, Kalandadze IV, Ramsden JJ, Mikeladze DG. Adhesive Properties and Inflammatory Potential of Citrullinated Myelin Basic Protein Peptide 45-89. Neurochemical Research. 37, no 9:1959-1966, 2012.
- Shanshiashvili LV, Dabrundashvili N, Natsvlishvili N, Kvaratskhelia E, Zhuravliova E, Barbakadze T, Koriauli S, Maisuradze E, Topuria T, Mikeladze DG. mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes. Molecular Immunology 51, no 3-4:310-315, 2012.
- Zhuravliova E, Barbakadze T, Jojua N, Zaalishvili E, Shanshiashvili L, Natsvlishvili N, Kalandadze I, Narmania N, Chogovadze I, Mikeladze D. Synaptic and Non-Synaptic Mitochondria in Hippocampus of Adult Rats Differ in Their Sensitivity to Hypothyroidism. Cellular and Molecular Neurobiology 32:1311–1321, 2012.
- Shanshiashvili L. N. Narmania T. Barbakadze E. Zhuravliova N. Natsvlishvili J. Ramsden, D. G. Mikeladze. S-Nitrosylation Decreases the Adsorption of H-Ras in Lipid Bilayer and Changes Intrinsic Catalytic Activity. Cell Biochemistry and Biophysics. 59:191–199, 2011.
- Shanshiashvili L., Suknidze N., Machaidze G., Mikeladze D., Ramsden J. “Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes“. Archives of Biochemistry and Biophysics. 419, 170-177, 2003.
Current Courses |
Course Catalog |
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| One-cycle higher educational program
Bachelor’s level
Master’s level
One-cycle higher educational program
Bachelor’s level
Master’s level
Doctoral level
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2020-2021 Year One-cycle higher educational program
Bachelor’s level
Master’s level
Doctoral level
2019-2020 Year One-cycle higher educational program
Bachelor’s level
Master’s level
2018-2019 Year Bachelor’s level
Master’s level
2017-2018 Year Bachelor’s level
Master’s level
2016-2017 Year Bachelor’s level
Master’s level
2015-2016 Year Bachelor’s level
Master’s level
2014-2015 Year Bachelor’s level
Master’s level
2013-2014 Year Bachelor’s level
Master’s level
2012-2013 Year Bachelor’s level
Master’s level
Doctoral level
2011-2012 Year Bachelor’s level
Master’s level
2010-2011 Year Master’s level
Doctoral level
2009-2010 Year Bachelor’s level
Master’s level
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